27 research outputs found

    A framework for e-government success from the user’s perspective

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    A thesis submitted to the University of Bedfordshire in partial fulfilment of the requirements for the degree of Doctor of PhilosophyThis thesis aims to contribute to a better understanding of e-government portal success by developing a e-government success framework from a user’s perspective. The proposed framework is underpinned by relevant theories, such as DeLone and McLean’s IS success model, the Technology Acceptance Model (TAM), self-efficacy theory and trust. The culture aspect has also been taken into consideration by adopting personal values theory introduced by Schwartz (1992). Three data collection methods were used. First, an exploratory study was carried to explore the main aspects and factors for understanding e-government systems success. Second, a Delphi study was conducted to investigate which of the ten value types are particularly relevant to success or have a significant impact. Third, a survey-based study was carried out to validate empirically the proposed theoretical framework. Results of the exploratory study helped to identify the potential success factors of e-government systems. The results of the Delphi study suggest that four of the ten values, namely self-direction, stimulation, security, and tradition, most likely affect e-government portal success. Structural equation modelling techniques were applied to test the research model using a large-scale survey. The findings of hypothesis testing suggested that e-government portal success (i.e. net benefit) was directly affected by actual use and user satisfaction and indirectly affect by a number of factors concerning system quality, service quality, information quality, perceived risk, and computer self-efficacy. By combining IS success model and TAM, this study found system quality, information quality and service quality affected the perceived ease of us, but service quality had no effect on perceived usefulness. However, perceived risk seemed to have no effect on attitudes towards using, but very small negative effect on perceived usefulness. Users’ computer skills was found to have no effect on perceived ease of use and very small effect on perceived usefulness. These indicate that risk and IT skills are playing less significant role in the context of e-government. The research findings confirmed that adoption was not equivalent to success, but it was the necessary precondition to success. In the personal values-attitude-behaviour model, the empirical evidence suggested that Conservation affects attitude towards use which, in turn, affects behavioural intention to re-use. Openness to change had no effect on attitude toward using. The findings provide important implications for e-government research and practice

    Identifying the relevance of personal values to e-government portals' success: insights from a Delphi study

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    Most governments around the world have put considerable financial resources into the development of e-government systems. They have been making significant efforts to provide information and services online. However, previous research shows that the rate of adoption and success of e-government systems vary significantly across countries. It is argued here that culture can be an important factor affecting e- government success. This paper aims to explore the relevance of personal values to the e-government success from an individual user’s perspective. The ten basic values identified by Schwartz were used. A Delphi study was carried out with a group of experts to identify the most relevant personal values to the e-government success from an individual’s point of view. The findings suggest that four of the ten values, namely Self-direction, Security, Stimulation, and Tradition, most likely affect the success. The findings provide a basis for developing a comprehensive e-government evaluation framework to be validated using a large scale survey in Saudi Arabia

    Influence of premolar extraction or non-extraction orthodontic therapy on the angular changes of mandibular third molars

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    Abstract Aim: To compare the angular changes of the third molars relative to the occlusal planeand to the second molar long axis in extraction group and compare these changes with a non extractiongroup.Materials and methods: The study included pre and post treatment panoramic radiographrecords of 90 subjects treated by first premolar extractions and 90 subjects who had been treatedwith non extraction orthodontic therapy (n=90). Two angular variables were measured. Firstly,the angle between the long axis of the third molar and the occlusal plane (M3–OP) and secondly,the angle between the long axis of the third molar and the long axis of the second molar (M3–M2).Data were analyzed by paired and student’s t-test.Result: The analyzed data to assess the changes in the third molar angulation from pretreatmentto post treatment did not vary significantly in both the groups (pdecreased angular values. The M3–OP angular difference was (7.3± 2.45) in extraction group ascompared to (5.85 ± 1.77) in non extraction group. The M3–M2 angular difference of (4.26±3.11) in extraction group and (2.98 ±1.74) in non-extraction group was observedConclusion: Extraction of premolars did not demonstrate considerable changes on the angulationof the third molars. The factors other than premolar extractions may influence the angulationof the third molars.</p

    Factors affecting the extent of utilization of physiotherapy services by physicians in Saudi Arabia

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    Purpose: To investigate physicians’ attitudes, opinions and experiences towards physiotherapy services as well as to identify the potential factors that may affect the extent of utilization of physiotherapy services (based on physicians’ beliefs) in Saudi Arabia (SA). Subjects and Methods: A cross-sectional study was conducted. Results: A total of 108 respondents met the inclusion criteria. The respondents’ attitude towards physiotherapy was slightly low (53.5%), while their opinions and experiences of physiotherapy indicated some important issues. For example, 50% of them believed that physiotherapists did not create a good awareness about physiotherapy services and 55.5% admitted that they did not have enough information about physiotherapy services. The most potential factor reported by physicians that may affect the extent of utilization of physiotherapy services was the lack of physiotherapist’s skills and knowledge to assess and treat patients (55.3%), followed by the limited knowledge of physicians regarding the types of physiotherapy services (44.5%) and the lack of cooperation between physicians and physiotherapists (40.7%). Conclusion: There were some factors that limited the extent of utilization of physiotherapy services in SA. Physiotherapy academics and clinicians should attempt to change physicians’ negative attitudes, promoting awareness to provide them with a better understanding of physiotherapy services

    Baicalin-Loaded Lipid&ndash;Polymer Hybrid Nanoparticles Inhibiting the Proliferation of Human Colon Cancer: Pharmacokinetics and In Vivo Evaluation

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    This research work is focused on pharmacokinetic and biochemical experiments to assess baicalin-loaded lipid&ndash;polymer hybrid nanoparticles (LPHNPs) with colon-targeting specificity. The nanoprecipitation method was used to develop the LPHNPs, and the characterized formulation revealed the 184.3 nm particle size, PDI of 0.177, spherical shape, and zeta potential of &minus;19.8 mV. The baicalin LPHNPs are said to be poorly absorbed in the stomach and small intestine, and in vitro drug release tests have shown that the drug is released mostly in the caecal fluid. Additionally, the LPHNPs showed stability and nonsignificant drug loss at 25 &deg;C for 3 months. The least viable population of baicalin-loaded LPHNPs was detected at a lower IC50 value after 48 h, and no cytotoxicity was observed by blank suspension and blank LPHNPs up to the concentration of 100 &micro;g/mL. Apart from this, the pharmacokinetics study showed that baicalin from LPHNPs is much less absorbed and least available in the blood plasma and maximum available in the colon. Concurrently, organ distribution studies demonstrated that baicalin-loaded LPHNPs were distributed more widely in the colon compared to baicalin suspension. Moreover, baicalin-loaded LPHNPs were found to be superior to a baicalin suspension in reducing elevated liver enzyme levels. In a nutshell, baicalin-loaded LPHNPs show superior efficacy and can be maximally localized into the colon rectal cancer along with systemic availability of the drug

    The awareness of healthcare staff towards post-stroke cognitive impairment: a cross sectional study

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    This study aimed to determine the awareness amongst healthcare staff of post-stroke cognitive impairment in a university teaching hospital and supporting stroke rehabilitation unit. [Subjects and Methods] A cross sectional study was employed to collect data from 20 healthcare staff about post-stroke cognitive impairment. This study was conducted in Ireland at two sites, the Acute Stroke unit in Cork University Hospital, and the Stroke Rehabilitation unit and Assessment and Treatment Centre in St. Finbarr’s Hospital. [Results] Approximately 75% of participants felt that they had knowledge about post-stroke cognitive deficits, with around 50% of them having patients with persistent cognitive decline between 40% and 60%. Most participants (70%) agreed that cognitive function should be routinely assessed and the majority (85%) discussed the potential impact of post-stroke cognitive deficits with patients and their families. However, some participants need to be aware of post-stroke cognitive deterioration. [Conclusion] Although there was evidence of good practice, a small number of healthcare staff felt that they did not have sufficient knowledge about post-stroke cognitive deficits. Thus, further professional education should be provided to improve the knowledge of healthcare staff about potential cognitive impairments after stroke
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